Consultancy Services
Assisting with Pharmaceutical Formulation and Development
We consult about all aspects of pharmaceutical formulation and development. CRISM Therapeutics has extensive resources, including a wide selection of remixers, available for our clients to develop and create new formulations.
Remixing and Extrusion
We offer remixers and extruders of various sizes, including the smallest commercially available twin-screw extruder (7.5mm, 15:1 L/D) in the UK. This allows for samples as small as 3 to 5 grams to be processed and permits easy and cost-effective development of new formulations and the rapid screening of polymer and API blends.
Furthermore, this process is followed by producing pre-production batches for scale-up and technology transfer on a 10mm, 40:1 L/D twin-screw equipped with various feed and take-off arrangements.
Full Tabletting Suite
Mixers
Granulators
Extruders and Spheronizers
Tablet Press and Coater
Parallel Plate Rheometer
Differential Scanning Calorimeter
Thermogravimetric Analyser
Texture Analysis for Bio-AdhesMaterial Characterisation
ion
Tensile Strength Melt Flow Indexer
Analysis
If any analysis is required, we provide UV, HPLC, GC, GPC, HPLC-MS, FT-IR, and Raman spectroscopy in addition to:
Particle Size Analysis
NMR and X-Ray Diffraction
Dissolution, Disintegration, Hardness and Friability Testing
Scanning Electron Microscope
Transmission Electron Microscopes
Fused Deposition Modelling
We also provide filament-fed and pellet-fed fused deposition modelling (FDM) 3D printers. Suitable for the manufacture of personalised medicines, multi-layered dosage forms, and complex devices, each of the printers has 4 print heads, allowing for up to four different drugs or formulations to be printed with the same digital form.